Researchers from IMICB-BAS and CPSBB protect a utility model for a new combination of natural bioactive compounds to support metabolic health
Scientists from the “Metabolomics” laboratory within the Department of Biotechnology at the “Stephan Angeloff” Institute of Microbiology of BAS led by Prof. Milen Georgiev, in collaboration with researchers from the Centre of Plant Systems Biology and Biotechnology (CPSBB), have protected a utility model for a newly developed combination of natural bioactive compounds comprising the isoflavonoid maackiain, the triterpene betulinic acid and the alkaloid piperine. The scientific results have been obtained during five years of pre-clinical studies using the model organism Caenorhabditis elegans and have been confirmed in experimental rodent models. The toxicological studies conducted found no toxic effects at the doses administered and under the experimental conditions. A clinical trial is due to be conducted to assess the effects of the developed combination on metabolic [...]
